5 – 5. Nuclear factor kappa B (NF-κB) transcription factors regulate several important physiological processes, including inflammation and immune responses, cell growth, apoptosis, and the expression of. Neurofibromatosis (NF) is a multisystem disorder and tumor predisposition syndrome caused by genetic mutation on chromosome 17-17q11. You are going to relax and be a bit couch-locked. CommonwealthNeurofibromatosis type 1 (NF1) is a multisystem disorder that primarily involves the skin and peripheral nervous system. If you’ve smoked this strain before, tell us about it by leaving a review. Cherry Punch is an evenly balanced hybrid strain (50% indica/50% sativa) created through crossing the classic Cherry AK-47 X Purple Punch strains. 2 In 2007, an NF1. Fish Scale is 25% THC, making this strain an. Congenital heart disease is the most frequent congenital disorder, affecting a significant number of live births. 5g | CAC” Cancel reply. The Durban Poison cannabis strain has earned the crown it carries as one of the most wanted sativas out there. Neurofibromatosis (NF) is a neurocutaneous syndrome characterized by the development of tumors of the central or peripheral nervous system including the brain, spinal cord, organs, skin, and bones. The THC content in this strain makes it. Family Guy Weed Episodes. visible neurofibromas that appear as bumps on or under the skin. Cannabis Resources. 7. NF1 is sometimes referred to as 'peripheral neurofibromatosis. 5. Leafly. Ready for a hard-hitting smash of delicious flavors and effects? Cherry Punch brings on both with an almost unforgiving level of potency. Overview: Super Silver Haze is a champion sativa strain that rose to fame by winning three consecutive High Times Cannabis Cups from ’97 to ’99. NEWSLETTER SIGN-UP. This explains why NF1 is included in the group of. A systematic literature review was. 002646 B6. Stress . Numerous mouse strains of Nf1 optic pathway glioma have been generated over the past 15 years by. I have purchased both of them multiple times. Sour Tsunami is a strain that became famous for being one of the first to be specifically bred for high CBD rather than THC content. Ready for a hard-hitting smash of delicious flavors and effects? Cherry Punch brings on both with an almost unforgiving level of potency. It consists of three syndromes: neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and schwannomatosis (SWN). Cannabis Flower NF-1 NF-1 by UpNorth Humboldt THC — CBD — Potency Product rating: 5. Description. (ExoA), the NF1 strain was determined to be. Because NF1 has many diverse manifestations, it is associated with significant morbidity and. Lucid Blue is a supremely potent sativa that will bring your thoughts to a new level of consciousness. 4 star. 2 in NF type 2. In multi-strain infections, the toxin produced by NF2 breaks down the muscle tissue and enables NF1 to travel to the bloodstream or organs. Neurofibromatosis type 1, or von Recklinghausen disease, is an autosomal dominant disease. Neurofibromatosis 1 (NF1) is the most common of the three conditions. NF1 is a potent hybrid with one of the most interesting – and impressive – genetic makeups to date. This review highlights the transition needs of NF1 patients and provides resources for both clinicians and families to facilitate HCT in this population. Details: Orange Gasm will curl your toes with an explosion of sweet oranges and tropical citrus flavors! Orange Gasm makes amazing orange flavored concentrates. View computational annotations. Initially, many describe their experience as one that’s intensely euphoric, as just a. Neurofibromatosis type 1 (NF-1) or Von Recklinghausen disease is one of the inheritable neurocutaneous disorders that also harbinger the risk for bone abnormalities, vasculopathy, and cognitive impairment. Chemdawg 91 is a popular hybrid bred from unknown parents - some theorize that the “91” in its name refers to the year of its creation. UpNorth- NF-1. About 8% of children with six or more café au lait spots and no other clinical features of NF1 have Legius syndrome [Evans et al 2016. Review Submitted 5 star. Fig Farms is based in Sonoma county, and is focused on growing in-house strains that they've meticulously bred through years of research & development. Neurofibromatosis type 1 (NF1) is a neurodevelopmental disorder in which affected children and adults are at a higher risk of sleep disorders. Get details and read the latest customer reviews about NF-1 by Northern Emeralds on Leafly. The disorder is characterized by considerable heterogeneity of clinical expression. 28, 2021, 4:54 a. Enter a delivery address. Get details and read the latest customer reviews about NF-1 by UpNorth Humboldt on Leafly. Discover NF1 weed and read reviews of the effects and feelings cannabis consumers report from this marijuana strain. East Coast breeders. Large neurofibromas can also arise fromStrain Name: C57BL/6JGpt-Nf1 em1Cflox /Gpt: Strain Number: T007997: Official Symbol: Nf1: Strain Strategy: T007997. Its frequency is approximately 1 per 3000 neonates, regardless of sex or ethnic background (). Exotic Genetix' Rainbow Chip is a THC dominant variety and is/was also available as feminized seeds. NF1 3. UpNorth NF-1. Vanilla Latte packs a super sweet and creamy vanilla coffee taste with a lightly spicy exhale. It is very crystallized & the smell is definitely there! Haven’t tried it yet will post after! Any comments feel free! This is absolutely one of the most underrated strains of last year, no question. Jokerz is an indica dominant hybrid strain (70% indica/30% sativa) created. 071). Mimosa is a sativa dominant hybrid strain (70% sativa/30% indica) created through crossing the classic Purple Punch X Clementine strains. The condition is called segmental NF1 when clinical features are limited to one area of the body due to somatic mosaicism of a. 28, 2021, 4:54 a. Nobody in Sac has this. NF1 is a hybrid, high-THC strain with parents that are readily recognized by any cannabis enthusiast: Northern Lights and Chemdawg. NF1 Strain Information, Effects, and Uses - Lantern. NF1 - Indica Hybrid - by UpNorth Cannabis - Strain Review - from Buds & Roses, Studio City CaWeedEntertainment. 1 However, due to difficulty in diagnosis and underreporting, this is likely an underestimation. Schizochytrium sp. An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1–NF4). Symptoms of NF1 range from very mild to quite severe. Summary. Neurofibromatosis (NF) is a neurocutaneous syndrome characterized by the development of tumors of the central or peripheral nervous system including the brain, spinal cord, organs, skin, and bones. Creative people love this strain, as. . low THC high THC. 0%. Neurofibromatosis type 1 (NF1) is a common genetic disorder. Eight-week-old rats were treated with loperamide, and then with 3. Customer Reviews. 1177/0883073817739509. Neurofibromatosis type 1 (NF1) is a common autosomal-dominant hereditary tumor predisposition syndrome with an incidence of ~1 in 3000 people worldwide. Thankfully, these two heavy indica strains of medical cannabis for neurofibromatosis are excellent for getting you off to sleep: Northern Lights. THC: 20%. We aimed to study the molecular spectrum of. 2 Patients with. An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1–NF4). Neurofibromatosis 1 (NF1), historically called von Recklinghausen’s disease, is a genetic disorder characterized by increased risk of developing noncancerous (benign) and cancerous (malignant) tumors, as well as various other physical and neurological manifestations. 81% total cannabinoids. NEA Dispensary In my home town421 subscribers in the CBDHERB community. NF1 strain is a delightful and flavorful cannabis strain that is sure to please your taste buds. low THC high THC. Successful inhibition of MEK for patients with neurofibromatosis type 1 and progressive optic pathway gliomas or plexiform. No description available. NF type 1 (NF1) is differentiated from central NF or NF type 2 in which patients demonstrate a relative paucity of cutaneous findings but have a high incidence of meningiomas and acoustic neuromas (which are frequently bilateral). Products. 5g | Union Twist | Sativa Hybrid | NF1 3. com users in 2021. Abstract. (B-Witched x B-Witched BX1): Named after the Greek god of wine and festivities, this flower aptly features a pleasing grape and cheese aroma and a sweet grape cheesecake flavor. . Neurofibromatosis type 1 (NF1) is most frequently confused with Legius syndrome, as some individuals with Legius syndrome fulfill the clinical diagnostic criteria for NF1 [NIH 1988, Gutmann et al 1997]. . 2 Patients with NF1 also have a life expectancy 10 to 15 years shorter. GTPase activator that negatively regulates Ras protein signal transduction and cAMP biosynthesis; involved in the cellular response to various stresses; localizes to the mitochondrion and the endoplasmic reticulum membrane. They also got in Headband, Garlic Breath (knocked me out), and Peanut Butter Aura from Trade Roots. At your first visit, a neurologist reviews these materials and your medical history with you. Our flowers are available in licensed retailers throughout California, Illinois, & Arizona in eighth and pre-roll form. A doctor or genetic counselor may gather information that indicates which members of the family have developed clinical manifestations of neurofibromatosis type 1 (NF1), such as. Stress. This review is based on literature search and the results of the clinical study “Craniofacial and Oral Alterations and Speech in patients with. No promise that’s what’s still in the jar by the time you get it. Dry mouth Helps with: Depression . With those admired genetics crossed we bring you NF1: a very strong hybrid indica dominant strain. With respective incidences of 1 in 3000, 1 in 33 000, and 1 in 60 000 births, they form part of the group of rare tumor-suppressor syndromes. Named for its amazing flavor, Red Velvet is the perfect mouthwatering bud for any indica love who. Pain. Their use of original landrace strains for. With earthy flavors of lemons and citrus, Amnesia Haze is the perfect sativa strain to start your day with a smile. Purchased 02/12/21 from Harborside. Neurofibromatosis (NF) is a genetic abnormality that affects the cell growth of neural tissue, leading to tumor growths that impact the skin, nervous system, eyes and other organs. 2 In 2007, an NF1. , 1996 and Williams et al. In a recent observational study, the estimated life expectancy for individuals with NF2 was 69. CommonwealthBlue Cheese marijuana is classified as an indica-dominant hybrid, with a roughly 80% indica and 20% sativa genetic profile. 2–10%) in the pregnant group and 5. The NF1 gene is located. The most common signs are found on the skin, typically in infancy or early childhood. 4. About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features Press Copyright Contact us Creators. Fifty percent of NF1 cases are hereditary and the remaining. 3 to 15 cases per 100,000 population. NF1 (aka NF-1) is a hybrid marijuana strain. I’m a fan. Content related to the Cannabis…Neurofibromatosis type 1 (NF1) is a complex multisystem disorder requiring lifelong medical surveillance, education, and psychosocial support. Lineage: Red Velvet S1. UPS AND SHORTS IN LINK ABOVE!Neurofibromatosis type 1 (NF1) is a rare, progressive, genetic condition characterized by benign tumors called plexiform neurofibromas (PN) that develop along nerve sheaths throughout the body, with signs and symptoms typically present at birth. In this study, a virulent strain A. The hallmarks of NF1 are the multiple café-au-lait macules and associated cutaneous neurofibromas. . Flavor is classic NL with candy gas finish. 1 Neurofibromatosis type 1 is caused by a germline NF1 tumor suppressor pathogenic or likely pathogenic variant. / I saw some stores in Worcester county that carry trade roots but couldn’t find this specific strain Reply. Neurofibromatosis type 1 (NF1) is an autosomal dominant condition, with a birth incidence of approximately 1:2000–3000, caused by germline pathogenic variants in NF1, a tumor suppressor gene encoding neurofibromin, a negative regulator of the RAS/MAPK pathway. It's covered separately as it has different symptoms and causes. In an effort to identify potential sleep disturbances in a small animal model, we used a previously reported Nf1 conditional knockout (Nf1 CKO ) mouse strain. Mother: Sunset Sherb. To identify the diagnosis, five affected probands with suspected NF from unrelated families were included in this study. 6 126 votes| 67 reviews. Like most marijuana strains, NF1 can be grown indoors and outdoors. The disorder is progressive, though variable; it will worsen. If you've smoked this strain before, tell us about it by leaving a review. The hallmarks of NF1 are the multiple café-au-lait macules and associated cutaneous neurofibromas. Espresso is a sativa-dominant hybrid marijuana strain. Effects: Giggles. With those admired genetics crossed we bring you NF1: a very strong hybrid indica dominant strain. It results from mutations of the NF1 gene and shows almost complete penetrance. 5g - Grown by: Trade Roots NF1 Strain is a hybrid with some very well-known parents—Northern Lights and Chemdawg. 4, 6–8 In this regard,. In a world. NF1 (aka NF-1) is a hybrid marijuana strain. Search, Click, Read and Increase your knowledge: ADULTS ONLY. The high has a subtle build of effects, sneaking into the brain slowly before lifting the spirits into a. more Notice Age-restricted video. Products. Neurofibromatosis type- 1 is a condition characterized by changes in skin coloring (pigmentation) and the growth of tumors along nerves in the skin, brain, and other parts of the body. It tends to deliver a more uplifting high with a mental uplift and energetic experience. This strain brings together the piney scent of Northern Lights with the diesel aroma of Chemdawg. 2 star. An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1–NF4). Aeromonas hydrophila is a Gram-negative bacterium that is commonly distributed in aquatic surroundings and has been considered as a pathogen of fish, amphibians, reptiles, and mammals. Hey bud, the strain Nf1 is new to us and we're still gathering information about it. Examination of the levels of Nf1 gene expression in mouse strains with differences in tumor susceptibility using quantitative polymerase chain reaction demonstrates that strain background has as much effect on N f1 expression levels as mutation of one Nf2 allele, indicating that studies of haploinsufficiency must be carefully interpreted with respect to. Lineage: Northern Lights x Chemdawg NF1 is a hybrid with some very well-known parents—Northern Lights and Chemdawg. NF1 is a cross of the classic Northern Lights and Chemdawg strains. The tumours are usually non-cancerous (benign) but may cause a range of symptoms. Fig Farms STRAINS. F1 is a super rare sativa dominant hybrid strain (70% sativa/30% indica) created through an unknown combination of other sativa heavy strains. Neurofibromatosis type 1 (NF1) is a multisystem disorder that primarily involves the skin and peripheral nervous system. Neurofibromatosis type 1 (NF1) is an incurable genetic condition that affects 1 in 3000 newborns worldwide. An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1-NF4). Iris Lisch nodules (benign growths on the colored part of the eye) Posted in Product Reviews, Strains | Tagged Aeriz, effects, flavor, NF-1 by UpNorth, NF-1 strain, NF-1 strain review, NF1 strain, UpNorth Review: 8 Inch Bagel Live Rosin by Aerīz Illinois News Joint Posted on March 20, 2023 by Michael Lasley March 21, 2023 Neurofibromatosis type 1 (NF1) is a condition caused by a change in a specific gene, and therefore can be inherited and passed on. A couple hits is all it takes for most patient's seeking this strain's powerful body effects, an upbeat mix of euphoria and physical relaxation. The effects of Frosty are more calming than energizing. The human disease von Recklinghausen's neurofibromatosis (Nf1) is one of the most common genetic disorders. If you are a regular cannabis user, there is a very high probability that you have tried either Northern Lights or Chemdawg strain. Of 56 patients undergoing pheochromocytoma resection, 6 (11%) had NF1. A great review should include flavor, aroma, effect, and helpful health ailments. Growing Marijuana. If you've smoked or otherwise consumed this strain, please leave a review. Only a select few have impressed me. Gelato is a hybrid crossed from taste-engineered parents Thin Mint Girl Scout Cookies and fruity indica Sunset Sherbert. 10 Most popular strains voted by Allbud. This was higher in. This cultivar offers long lasting. Reputation: One review reads, “A FAVORITE OF COURSE💖 This is the top dog of. Today we check out NF-1 from UpNorth. 2 in NF type 1 (NF1), and on chromosome 22-22q12. Genotype–phenotype relationships provide an approach to understand the pathogenesis and development of NF1. Edited by Caroline S. 9 ± 2% vs -25. Introduction. NF1 is a rare indica dominant hybrid strain (80% indica/20% sativa) created through crossing the classic Northern Lights X Chemdawg strains. But when the strains were. The diagnosis is based on a variety of clinical fea-tures [3] (Table 1). NF1 causes tumours to grow on nerves. NF1 - Indica Hybrid - by UpNorth Cannabis - Strain Review - from Buds & Roses, Studio City Ca - YouTube 0:00 / 4:49 Sign in to confirm your age This video may. Okay this is the bud that actually made me start to want to write some more reviews after a long break. Figment. 1 In 1987, the National Institutes of Health (NIH) developed a consensus for diagnosis due. Gaining insights into its genetic etiology could lead to a deeper understanding of this condition. They give rise to a greater tumor burden for. IN THE PRESS. Plexiform. Johannessen et al. advertise on Leafly. Member Berry produces a long-lasting high with happy and euphoric effects. NF1 is one of two disorders referred to collectively as the “neurofibromatoses,” the other being NF2 . 93). We're still learning about the flavors and effects of NF1. fowleri NF_NF1 and NF_AR12 have approximately the same number of genes as N. 7%. Very nice if I do say so myself. Review: NF-1 by UpNorth. NF1 (Neurofibromin 1) is a Protein Coding gene. Type II neurofibromatosis (NF2; 101000) is a genetically distinct disorder caused by mutation in the gene encoding merlin (NF2; 607379) on chromosome. Pain. calming energizing. It can affect many organs and. CONTACT. When the strains occur together, the story is reversed. Consumers who have smoked this. A handful of bright turf green flowers coated with a dense. NF1: “NF1” almost sounds like what you might name your first racecar and it is a fitting title! “NF1” is a Sativa-Dominant strain said to be perfect for day-time activities. Robert Bergman is an Amsterdam-based marijuana grow expert who has years of experience from small grows to massive operations. Our NF1 strain review focuses on the sativa variety since the indica version is proprietary. the focus of this review will be on naturally occurring splice variants. Numerous mouse strains of Nf1 optic pathway glioma have been generated over the past 15 years by. NF is divided into two primary subgroups: neurofibromatosis type 1 (NF1), also known as von Recklinghausen or peripheral neurofibromatosis; and. MAP/ERK kinase 1 and 2 (MEK 1/2) inhibitors (MEKi) are investigated in several trials to treat lesions that arise from pathogenic variants of the Neurofibromatosis type 1 and type 2 genes (NF1, NF2). Effects. PMCID: PMC4918700. Lineage: Northern Lights x Chemdawg. Most NF1 patients are predisposed to benign peripheral nerve sheath tumors (PNSTs), including cutaneous neurofibromas (CNFs) and plexiform neurofibromas (PNFs). Approximately 30% of NF1 patients will meet one of the below criterion by the age of 1 year, 97% of patients will meet two criteria by the age of 8 years and, in a retrospective review of NF1 patients, all patients met the criteria by the age of 20 years. A lot of sativas exacerbate my anxiety but the J1 gives me the perfect calming buzz. Users note that this strain offers a strong one-two punch of both cerebral and physical effects, making her ideal for a late afternoon or early evening smoke session. The remainder of this. Progress in molecular biology and neuroimaging and the development of mouse models have helped to elucidate the aetiology of NF1 and its. Find information about the Figment strain from Fig Farms such as potency, common effects, and where to find it. Feelings. This batch of flower tested at 0. NF1 is the most common type of neurofibromatosis and the most common of the phakomatoses, a group of congenital neurocutaneous disorders. May express fruity or diesel-smelling phenotypes. The μ1-encoding M2 gene is genetically linked to strain-specific differences in apoptosis-inducing capacity, suggesting a function for μ1 in induction of death signaling. . '. The main clinical features are café-au-lait spots, iris. Stress. Dry mouth Helps with: Depression . calming energizing. NF1 has a lower incidence of central nervous system (CNS) tumors than NF2. low THC high THC. Aroused. The condition is called segmental NF1 when clinical features are limited to one area of the body due to somatic mosaicism of a. Neurofibromatosis type 1. Jokerz Reviews. 5g - Union Twist - 3. Bedford Grow Strain List May 2023. S. Neurofibromatosis type 1 (NF1) (OMIM#162200) is a multisystem autosomal dominant disorder that primarily occurs due to underpinning pathogenic variants in the Neurofibromin gene (NF1;OMIM# 613113. 30. NF1 reviews 4. Effects of HLp-nF1 on a small intestinal transit parameter in a loperamide-induced constipation rat model. Lemon Thai produces high yields both indoors and outdoors but appreciates a lot of space to grow. NF1 is a Sativa with some very well-known parents—Northern Lights and Chemdawg. Stress . Energetic. NF1) [Virdis et al. NF1 (aka NF-1) is a hybrid marijuana strain. Strain: This Sativa-dominant hybrid (60% Sativa / 40% Indica) contains 17% to 24% THC, 2% CBD, and 1% CBN. Not all people with NF1 inherit the disease. calming energizing. While the NF2, NF3, and NF4 strains were clonal and possessed exotoxin A (ExoA), the NF1 strain was determined to be phylogenetically distinct, harboring a unique type 6 secretion system (T6SS) effector (TseC). The incidence of segmental NF1 is unknown, but the prevalence is. However, tumor diameters increased more than 20% per year in four neurofibromas in the pregnant group and in one neurofibroma in the control group ( P = 0. Yield: Generous Yields. Northern Emeralds. 5, P8 and 2 months were used to determine mass (g). Specifically, Happy Dreams Genetics’ Sour Lemon. Diseases associated with NF1 include Neurofibromatosis-Noonan Syndrome and Neurofibromatosis, Type I . Packaged 12/15/20. NF-1 by UpNorth, NF-1 strain, NF-1 strain review, NF1 strain, UpNorth. Vanilla, also known as “ Vanilla Bean ” or “ Vanilla Kush ,” is an indica dominant hybrid (70% indica/30% sativa) strain created through the potent cross of Kashmir X Afghani. About this product. If. Reported by 57 real people like you. com Strain ReviewName: NF1Strain Type: Indic. Many NF1 patients have been genotyped but few allele-phenotype correlations have been identified. calming energizing. Best known for its super delicious flavor, Wedding Mints #11 packs a soothing, well-balanced high and a great taste into each and every toke. The complications are diverse and disease expression varies, even within families. . Neurofibromatosis type 1 (NF1) is an incurable genetic condition that affects 1 in 3000 newborns worldwide. The term “neurofibromatosis” was derived from “neurofibroma,” the term used by von Recklinghausen to describe the benign nerve sheath tumor that is the hallmark of NF1. Inspired. Wedding Mints #11 is an evenly balanced hybrid strain (50% indica/50% sativa) created through crossing the delicious Wedding Cake X Thin Mint Girl Scout Cookies strains. One abnormal gene causes each form. If you have any info on this strain, drop us some knowledge at strains@iheartjane. 1 Although reported incidences vary, NF1 is estimated to occur in approximately 1 out of. Frosty, also known as “Frosty OG,” is an indica-dominant hybrid marijuana strain bred from unknown lineage. Relevant genotype–phenotype correlations have recently emerged, but only few pertinent studies are available. NF1 has a strong diesel scent to. It is descended from the legendary Chemdawg strain which is thought to be crossed from Thai and Nepalese landraces by U. Trains well as a multi. A tasty sativa strain from DNA genetics, Sour Kosher is a cross between the famous “AJ” cut of Sour Diesel and their very own award. 5C), only NF1 strains were detected and the average bacterial counts were 1. Seriously, I had a 25% batch of NF-1 and a 34% batch of Floracal's Morning Dew and the NF-1 kicked the shit out of it. Molecular Function. In addition, NF1 carries an 8% to 13% lifetime risk of developing malignant peripheral nerve sheath tumors. Find information about the NF-1 Premier Flower strain from UpNorth Humboldt such as potency, common effects, and where to find it. Once this mutation has occurred, the abnormal gene can be inherited. This strain brings together the piney scent of Northern Lights with the. Neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and schwannomatosis (SWN) are three clinically distinct tumor predisposition syndromes with a shared tendency to develop peripheral and central nervous system neoplasms. Conclusions Patients with NF1 treated with selumetinib may experience subtle changes in systolic function identied by global longitudinal strain and not revealed by left ventricular ejection fraction. NF1. NF1 is a hybrid, high-THC strain with parents that are readily recognized by any cannabis enthusiast: Northern Lights and Chemdawg. Large deletions of the NF1 gene and its flanking regions are associated with a more severe NF1 phenotype than the NF1 general population. NF1 is a rare indica dominant hybrid strain (80% indica/20% sativa) created through crossing the. Although its exact parentage is kept a closely guarded secret by its breeders, F1 is often sought out for its super high level of potency and giddy daytime effects that make for the perfect. STRAINS. No promise that’s what’s still in the jar by the time you get it. Irie Genetics' Orange Gasm Description. On the one hand, NF1 is a genetic disorder resulting from mutations in the NF1 gene. 2 of chromosome 17. It is the most frequent of the so-called hamartoses. Neurofibromatosis (NF) encompasses a group of distinct genetic disorders in which affected children and adults are prone to the development of benign and malignant tumors of the nervous system. Known for its super heavy potency and long-lasting full-bodied effects, NF1 is perfect for any experienced patient who needs a little extra power behind their medicine. line derived from strain 129/OLA and knocked in an in-frame. It was the most common strain I ran across living in Oregon back in the late-mid ‘90s.